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The series consists of records created by the Commission on the Epidemic Outbreak of Small-Pox, 1892-1893.

The records include transcripts of evidence, exhibits, commissioner's notes, printed matter, a manuscript report and other miscellaneous documents related to the Commission.

The notebook of Judge Begbie also contains notes regarding several other commissions which he was involved in between 1891 and 1894.

The series consists of files kept by Provincial Health Officer, Dr. Henry Esson Young, from 1924 to 1939. The files relate mostly to outbreaks of disease, including smallpox, infantile paralysis (poliomyelitis), plague, trachoma, tick paralysis, psittacosis, and leprosy. The files contain correspondence of the Provincial Health Officer with Medical Health Officers in B.C. and the U.S. Public Health Service about outbreaks of infectious disease, including the 1932 smallpox epidemic in Vancouver and recurring incidents of diphtheria at the Queen Alexandra Solarium. They also include reports relating to lab services.